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Matthew D Layne Selected Research

Acute Lung Injury

5/2010Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia.

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Matthew D Layne Research Topics

Disease

8Inflammation (Inflammations)
11/2020 - 01/2002
8Fibrosis (Cirrhosis)
10/2020 - 03/2009
5Endotoxemia
10/2018 - 07/2003
5Neointima
11/2014 - 04/2002
4Vascular System Injuries
01/2021 - 12/2005
4Atherosclerosis
02/2015 - 05/2002
3Sepsis (Septicemia)
10/2018 - 10/2003
3Pulmonary Fibrosis (Fibrosing Alveolitis)
12/2011 - 05/2006
2Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos)
10/2020 - 01/2018
2Vascular Remodeling
03/2014 - 09/2003
2Vascular Diseases (Vascular Disease)
08/2012 - 09/2003
2Critical Illness (Critically Ill)
05/2010 - 02/2009
2Infarction (Infarctions)
03/2005 - 02/2002
2Reperfusion Injury
03/2005 - 02/2002
1Abdominal Aortic Aneurysm
04/2022
1Breast Neoplasms (Breast Cancer)
02/2022
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
01/2021
1Pulmonary Atelectasis
11/2020
1Abdominal Obesity
01/2019
1Glucocorticoid Receptor Deficiency
01/2019
1Hyperplasia
01/2018
1Hypertrophy
01/2018
1Systemic Scleroderma (Systemic Sclerosis)
01/2015
1Sclerosis
01/2015
1Hypertension (High Blood Pressure)
08/2012
1Lung Diseases (Lung Disease)
06/2012
1Chronic Obstructive Pulmonary Disease (COPD)
03/2012
1Gastroschisis
07/2010
1Acute Lung Injury
05/2010
1Idiopathic Pulmonary Fibrosis
03/2009
1Infections
02/2009
1Myocardial Ischemia (Ischemic Heart Diseases)
03/2005
1Diabetes Complications
03/2005
1Hypercholesterolemia
09/2003
1Emphysema
05/2002
1Ischemia
02/2002
1Myocardial Infarction
02/2002

Drug/Important Bio-Agent (IBA)

16Proteins (Proteins, Gene)FDA Link
04/2022 - 02/2002
7CarboxypeptidasesIBA
01/2021 - 03/2009
6CollagenIBA
01/2021 - 03/2009
5Cysteine (L-Cysteine)FDA Link
04/2022 - 12/2005
5Heme Oxygenase-1IBA
06/2012 - 01/2002
4Transcription Factors (Transcription Factor)IBA
01/2015 - 09/2004
4Nitric Oxide Synthase (NO Synthase)IBA
02/2009 - 10/2003
3Extracellular Matrix ProteinsIBA
10/2020 - 01/2014
3EndotoxinsIBA
10/2018 - 07/2003
3myocardinIBA
01/2015 - 12/2011
2Heme (Haem)IBA
11/2020 - 06/2012
2Reactive Oxygen Species (Oxygen Radicals)IBA
11/2020 - 03/2005
2LipopolysaccharidesIBA
11/2020 - 10/2003
2CytokinesIBA
03/2014 - 08/2012
2Bleomycin (Blenoxane)FDA LinkGeneric
01/2014 - 03/2009
2DNA (Deoxyribonucleic Acid)IBA
05/2010 - 09/2004
2stallimycinIBA
05/2010 - 09/2004
2EnzymesIBA
03/2008 - 10/2003
2Actins (F Actin)IBA
09/2003 - 04/2002
1Angiotensin IIIBA
04/2022
1Collagen Type I (Type I Collagen)IBA
02/2022
1GelsIBA
02/2022
1InterferonsIBA
11/2020
1Carrier Proteins (Binding Protein)IBA
10/2020
1GlucocorticoidsIBA
01/2019
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
10/2018
1FibrinIBA
10/2018
1oxidized low density lipoproteinIBA
02/2015
1perlecanIBA
02/2015
1NexusIBA
08/2012
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
08/2012
1SmokeIBA
06/2012
1Silicon Dioxide (Silica)FDA LinkGeneric
06/2012
1AsbestosIBA
06/2012
1Air Pollutants (Pollutants, Air)IBA
06/2012
1Sp3 Transcription FactorIBA
03/2012
1Messenger RNA (mRNA)IBA
03/2012
1P-SelectinIBA
05/2010
1DiscoidinsIBA
03/2009
1LigandsIBA
02/2009
1Telomerase (Telomerase Reverse Transcriptase)IBA
05/2006
1Blood Glucose (Blood Sugar)IBA
03/2005
1Protein Isoforms (Isoforms)IBA
10/2003
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2003
1CholesterolIBA
09/2003
1Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA
09/2003
1Apolipoproteins E (ApoE)IBA
09/2003
1ApolipoproteinsIBA
09/2003
1Interleukin-10 (Interleukin 10)IBA
07/2003
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
07/2003
1cathepsin SIBA
05/2002
1invariant chain (Ii-Key)IBA
05/2002
1Interleukin-1beta (Interleukin 1 beta)IBA
02/2002
1Therapeutic UsesIBA
02/2002

Therapy/Procedure

5Therapeutics
01/2019 - 02/2002
2Ligation
11/2014 - 02/2002
1Thoracotomy
11/2020
1Tissue Expansion
01/2018